On July 1, 2018, news flooded about an act of love and humanity which could restore the lost hope. It was about a 3-year-old Skye Savren-McCormick, who proudly tossed flowers down the aisle for her 26-year-old Hayden Hatfield Ryals bone marrow donor. Giving life to the 3 year old, through such acts gives us the motivation to be one ourselves.
So let’s see the whole details on bone marrow, bone marrow transplant, what’s the procedure, advantages and disadvantages. And for the detailed information on bone marrow transplant meet with Abu Dhabi medical center at the earliest.
What is a Bone Marrow?
A bone marrow is the spongy soft, gelatinous tissue that’s present in some of the bones along with the hips and the thigh bones. It fills the centers of the bones or medullary cavities.
There are two types of bone marrow:
- Red bone marrow or myeloid tissue: is exceedingly vascular fibrous tissue and fragile, that contains hematopoietic stem cells. They are the blood-forming stem cells.
- Yellow bone marrow is known as fatty tissue: these contain mesenchymal stem cells or marrow stromal cells and produce cartilage, fat and bone.
Both of these types are enriched with blood vessels and capillaries. Bone marrow contains immature cells which is called as stem cells and it’s their function to develop into RBC, WBC and platelets.
Red Blood cells or RBC carries oxygen throughout the body. White Blood Cells or WBC provides immunity and fight against infections and Platelets helps the blood to clot when in injury. Visit the specialized medical hospital in UAE at the earliest for checking your count of the blood cells.
Bone marrow also comprises of hematopoietic stem cells or HSCs, they are the immature blood-forming stem cells. These produce new blood cells throughout one’s life span. Most cells are as of now differentiated and can only make duplicates of themselves. Nonetheless, these stem cells are unspecialized, which means they can possibly multiply through cell division and either remain as stem cells or get mature into the different types of blood cells.
What is bone marrow transplant?
The medical procedure that involves the replacement of damaged or destroyed bone marrow, by healthy bone marrows are termed as bone marrow transplant. The stem cells are transplanted, then it travels to the bone marrow and produces new blood cells and helps in the growth of new marrows. With the help of such transplantation, the body gets equipped with enough WBC, RBC and platelets to provide immunity against infections, reduce the chances of anemia and bleeding disorders respectively.
The healthy stem cells can be provided by a donor or from your own body. The stem cells are harvested, grown before chemotherapy or radiation therapy so that there are minimal chances of complications. If you want to get yourself registered for being a bone marrow donor then stopover the Abu Dhabi medical center.
What are the factors that lead to bone marrow transplant?
- Aplastic anemia: the disorder where marrow stops developing new blood cells.
- Cancer: lymphoma, leukemia and multiple myeloma
- Chemotherapy: bone marrow gets damaged by chemo
- Congenital neutropenia: the inherited disorder causing recurring infections
- Sickle cell anemia: the inherited disorder causing sickle-shaped RBC
- Thalassemia: the inherited disorder where the body develops abnormal hemoglobin
Be healthy yourself, if you feel any disadvantage or ill feelings meet with Abu Dhabi medical center and get yourself examined properly and completely.
What are the types of bone marrow transplant?
- Autologous Transplants
Autologous transplant utilization an individual’s own stem cells. It involves harvesting or reaping of your own bone marrow, before starting the harming treatments to cells like chemotherapy or radiation. After the treatment is done, your own particular cells come back to your own body.
This kind of transplant isn’t generally accessible. It must be utilized on the off chance which is if you have a healthy bone marrow. This reduces the chances of serious complications, including GVHD.
- Allogeneic Transplants
Allogeneic transplant includes the utilization of cells from a donor. The contributor must be a nearby hereditary match or genetic. Frequently, a perfect relative is the best decision, however, hereditary matches can likewise be found from a donor’s registry.
Allogeneic transplants are essential in the situation, when you have a condition that has harmed your own bone marrow cells. But such transplants bring in a higher danger of specific complexities, for example, GVHD. You’ll likewise presumably should be put on meds to suppress your immune system so that your body doesn’t attack the new cells. This can leave you vulnerable to diseases.
The accomplishment of an allogeneic transplant relies upon how intently the donor cells match your own.
The procedure of bone marrow transplant are:
At the point when your specialist finds out you’re prepared, you’ll have the transplant. The technique is like a blood transfusion.
In case you’re having an allogeneic transplant, bone marrow cells will be collected from your donor a day or two preceding your procedure. On the off chance that your own particular cells are being utilized, they’ll be recovered from the undeveloped cell bank. Specialized medical hospitals in UAE will have all the facilities to store and recover such stem cells.
Cells are gathered in two different ways.
Bone marrow harvest:
Amid a bone marrow harvest, cells are gathered from the two hipbones through a needle. You’re under anesthesia for this technique, which means you’ll be snoozing and free of any pain.
For Leukapheresis, a donor is given five shots to help the stem cells move from the bone marrow into the circulatory system. Blood is then drawn through an intravenous (IV) line, and a machine isolates out the white platelets that contain stem cells. This is the painless procedure from the above but requires a lot of resources, so encounter the Abu Dhabi medical center for this procedure.
To the patient:
A needle called central venous catheter or a port will be introduced on the upper right bit of your chest. This permits the liquid containing the new stem cells to stream straightforwardly into your heart. The stem cells then scatter all through your body. They move through your blood and into the bone marrow. They’ll establish and starts to develop.
The port is left on the chest, as the bone marrow transplant is done over few sessions for a couple of days. Numerous sessions give the new stem cells the most obvious opportunity to coordinate themselves into your body. That procedure is known as engraftment. The specialized medical hospital in UAE will provide you will the facilities required for such treatments.
Through this port, you’ll likewise get blood transfusions, nutrients, and liquids. You may require drugs to fight off diseases and help the new marrow develop. This relies upon how well you handle the medicines. Amid this time, you’ll be closely checked for any inconveniences.
Be a bone marrow donor today itself and save at least one person’s life. The feeling is amazing, just try it.